16th Annual Arthur H. Briggs Lectureship September 30, 2009:
Regulation of signaling receptors by endocytic membrane traffic
Dr. Arthur H. Briggs served as Chair of the Department of Pharmacology at UTHSCSA from 1968 - 1993, during which time he studied the actions of drugs on the cardiovascular system, hypertension, and drugs of abuse. His laboratory published the first papers on the central role of calcium in vascular smooth muscle contraction and the interrelationships between sodium and potassium ions and drugs. These studies led to important advances in the understanding of calcium in smooth muscle function.
Since his retirement in 1993, Dr. Briggs has remained Professor Emeritus within the Department and an annual lectureship has been held in his honor. This year our guest lecturer will be Mark Von Zastrow, M.D., Ph.D., Associate Professor of Psychiatry and Cellular and Molecular Pharmacology at the University of California, San Francisco.
Mark Von Zastrow, M.D., Ph.D.
Dr. Zastrow shares a few words on his lab’s website regarding one of the group's current interests, “Our laboratory is studying how various signal-transducing receptors and receptor-interacting proteins are regulated by membrane trafficking. A main focus of our present work is on regulated endocytosis of G protein-coupled receptors (GPCRs), particularly catecholamine receptors and opioid peptide receptors.”
PREVIOUS BRIGGS LECTURERS:
Dr. Perry Molinoff, 1994
Dr. Michael Moskowitz, 1995
Dr. Ian Creese, 1996
Dr. Lee E. Limbird, 1997
Dr. Ira Black, 1998
Dr. Henry Bourne, 1999
Dr. William A. Catterall, 2000
Dr. Raymond J. Dingledine, 2001
Professor James Black, 2002
Dr. David J. Triggle, 2003
Dr. Brian Kobilka, 2004
Dr. G. Stanley McKnight, 2005
Dr. Terry Kenakin, 2006
Dr. Marc Caron, 2007
Dr. Tomas Hökfelt, 2008