Office: 210-567-8505
Email: ashepherd@uthscsa.edu

The Division of Clinical Pharmacology is based in the Departments of Pharmacology and Medicine and occupies offices and patient and analytical areas in the McDermott Building. The clinical commitment includes the Hypertension Service of the University Medical System. Clinical studies are based on this patient population.

Selected Publications

Stagni G, O'Donnell D, Liu YJ, Kellogg DL, Morgan T, Shepherd AM. Intradermal microdialysis: kinetics of iontophoretically delivered propranolol in forearm dermis. J Control Release. Feb 3;63(3):331-9, 2000.

Jamieson MJ, Gonzales GM, Jackson TI, Koerth SM, Romano WF, Tan DX, Shepherd AMM. Evaluation of the IITC tail cuff blood pressure recorder in the rat against traarterial pressure according to criteria for human devices. Am J Hypertens 10(2):209-16, 1997.

Oparil S, Kobrin I, Abernethy DR, Levine BS, Reif MC, Shepherd AMM. Dose-response characteristics of mibefradil, a novel calcium antagonist, in the treatment of essential hypertension. Am J Hypertens 10(7 Pt 1):735-42, 1997.

Stagni G, Shepherd AMM, Liu Y, Gillespie WR. Generalized models of drug response kinetics: characterization and predition of verapamil pharmacodynamics with respect to plasma concentration or input-rate. 1997

Stagni G, Shepherd AMM, Liu Y, Gillespie WR: Bioavailability assessment from pharmacologic data: methods and clinical evaluation. J Pharm Biopharmaceutics 25(3):157, 1997.

Liu, YJ, Stagni G, Judith G. Walden, B.S. Shepherd AMM, Lichtenstein MJ. Thioridazine Dose-related Effects on Biomechanical Force Platform Measures of Sway in Young and Elderly Men. Journal of the American Geriatrics Society. 1997.