INTD 5067 - Introduction to Bioinformatics and Computational Biology

Course Director: Dr. Stephen Harris

Semester(s) Offered: Spring

Credits: 2

Course Description:

This course consists of 15 tutorials and lectures (2 hours each) covering the following topics:

R and Bioconductor, homology analysis, functional clustering, network analysis
Genomic tools, ensemble databases
Protein families, similarity searches
Methods in genotyping mammals
Statistical analysis and reduction of illumina and affymetrix microarray expression data
Genome-wide mapping of chromatin states using rapid DNA sequencing methods
Evolutionary filtering of DNA sequences, ENCODE Project
HapMap Tools
Applications for high performance computing in Biology
New computational tools for construction of system level understanding of biological processes
Mathematical models built on experimental and theoretical analysis of signaling pathways
Use of engineering principles to model the control structure of genetic networks
3D protein structure determination and prediction
Proteomics in biomedical research
Translational bioinformatics