NEUROSCIENCE GRADUATE STUDENTS

Simon Levy

 
Simon Levy

Hometown

Däniken, Switzerland


Education

MS, Life Science and Technologies, Neuroscience focus

BS, Life Science and Technologies

Ecole Polytechnique Fédérale de Lausanne (EPFL) - Lausanne, Switzerland


Lab Association

Bess Frost, Ph.D.


Hobbies and Interests

Hiking, Video Games, Politics and Skiing


Research

Tauopathies, the most common of which is Alzheimer’s disease, are characterized by the accumulation of tau protein in the brain. Alterations in the nuclear envelope structure have been shown to occur in human Alzheimer's disease brain tissue and in transgenic fruit fly models of tauopathy. Simon’s research focuses on investigating the effects of these changes on the nucleocytoplasmic RNA export machinery to elucidate possible pathogenic mechanisms of mutant tau protein.



• Accomplishments, Awards and Honors •

Award for best Master Thesis in Neuroscience - 2015



• Books and Publications •

Korecka, JA, Levy, S and Isacson, O (2016) In vivo modeling of neuronal function, axonal impairment and connectivity in neurodegenerative and neuropsychiatric disorders using induced pluripotent stem cells Mol Cell Neurosci Jun;73:3-12. doi: 10.1016/j.mcn.2015.12.004. Epub 2015 Dec 10



• Lectures, Posters and Presentations •

Society for Neuroscience Annual Meeting - San Diego, CA. - November 2016

Korecka, JA., Tablot, S., Levy, S., de Leeuw, SM., Terpstra, ML., Osborn, TM., Hallett, PJ., Jodelka, FM., Woolf, CJ., Hastings, ML., Isacson, O. : Dysregulation of ER stress response and calcium homeostasis in human iPSC-derived neurons carrying LRRK2 G2019S mutation (Poster)

Moloney, EB., Levy, S., Korecka, JA., Isacson, O. and Hallett, PJ. : Altered lysosomal stress markers in idiopathic Parkinson’s disease and following pharmacological-induced lysosomal dysfunction via glucocerebrosidase inhibition (Poster)


Society for Neuroscience Annual Meeting - Chicago, IL. - October 2015

Korecka, JA., Levy, S., Terpstra, ML., Dinesh, DC., Christensen, DP., Osborn, TM., Hallett, PJ., Jodelka. FM., Hastings, ML., Isacson, O. : Mitochondrial dysfunction and ER stress response in human iPSC-derived neurons carrying LRRK2 G2019S mutation (Poster)


Cell Symposia Multifaceted Mitochondria Conference - Chicago, IL. - July 2015

Korecka, JA., Levy, S., Terpstra, ML., Dinesh, DC., Christensen, DP., Osborn, TM., Hallett, PJ., Isacson, O. : Mitochondrial dysfunction in human iPSC-derived neurons carrying LRRK2 G2019S mutation (Poster)


Harvard Stem Cell Meeting (HSCI) - Boston, MA. - May 2015

Korecka, JA., Levy, S., Osborn, TM., and Isacson, O. : Neurite outgrowth and axon guidance molecules in Parkinson’s disease (Poster)