PHARMACOLOGY GRADUATE STUDENTS

Peter LoCoco

 
Peter LoCoco

Hometown

Fort Worth, Texas


Education

BS, Biology

BS, Biochemistry

Texas Christian University - Fort Worth, Texas


Lab Association

William Clarke, Ph.D.

Susan Mooberry, Ph.D.


Hobbies and Interests

Golf, Soccer, Football, Politics, Movies, World Events, Technology and Philosophy


Research

Peter's work focuses on the mechanisms underlying chemotherapy-induced peripheral neuropathy, specifically that caused by microtubule-targeting agents (e.g., paclitaxel). These agents are known to directly damage peripheral sensory neurons in cancer patients, which consequently leads to the development of debilitating pain and numbness. This condition is also dose-limiting, meaning that patients are forced to discontinue life-saving treatment, putting them at even greater risk for relapse or mortality. By understanding how these drugs cause peripheral neuropathy, we can then design novel treatment/preventative approaches to alleviate this condition. Furthermore, next-generation anticancer drugs can be better designed to maximize anticancer efficacy and minimize neurotoxicity.



• Accomplishments, Awards and Honors •

American Society for Pharmacology and Experimental Therapeutics(ASPET) Travel Award - Experimental Biology(EB) 2014 Meeting in San Diego, CA. - Feb 2014
'B2 bradykinin receptor-expressing nociceptors are differentially sensitive to the microtubule-targeting agent, paclitaxel'


Institute for Integration of Science and Medicine (IIMS) Translational Science Training Fellowship - UTHSCSA - June 2013-14
'Effects of Microtubule-Targeting Agents on Pain-Sensing Neurons'


Received the Greehey Graduate Fellowship in Children’s Health - October 2012



• Books and Publications •

Grad Student Peter LoCoco Organizes the Inaugural CIPN Symposium - The Pipette Gazette - March, 2015