PHARMACOLOGY POSTDOCTORAL FELLOWS
Jennifer Donegan
 
Selected Publications
  • Donegan, J.J., Boley, A.M., and Lodge, D.J. (2018) Stem cell derived interneuron transplants in a rodent model of autism Neuropsychopharmacology Article accepted
  • Donegan, J.J. and Lodge, D.J. (2017) Perineuronal nets in the ventral hippocampus are required for the long-lasting antidepressant effects of ketamine Int J Neuropsychopharmacol. Apr 1;20(4): 354-358 doi: 10.1093/ijnp/pyw095 PMID: 27806991
  • Donegan, J.J. and Lodge, D.J. (2017) Cell-based therapies for the treatment of schizophrenia Brain Res. Jan 15;1655: 262-269 doi: 10.1016/j.brainres.2016.08.010. Epub 2016 Aug 18. PMID: 27544423
  • Donegan, J.J., Tyson, J.A., Branch, S. Y., Beckstead, M.J., Anderson, S. A., Lodge, D.J. (2017) Stem cell derived interneuron transplants as a treatment for schizophrenia: preclinical validation in a rodent model Mol Psychiatry Oct;22(10): 1492-1501 doi: 10.1038/mp.2016.121. Epub 2016 Aug 2 PMID: 27480492
  • Carreno, F.R., Donegan, J.J., Boley, A.M., Shah, A., DeGuzman, M., Frazer, A., and Lodge, D.J. (2016) Activation of a ventral hippocampus-medial prefrontal cortex pathway is both necessary and sufficient for an antidepressant response to ketamine Mol Psychiatry. Sep;21(9): 1298-308 doi: 10.1038/mp.2015.176. Epub 2015 Dec 1. PMID: 26619811
  • Selected Abstracts
    Donegan, J.J., Boley, A.M., Lodge, D.J. Embryonic Stem Cell Transplants as a Therapeutic Strategy in a Rodent Model of Autism - Society for Neuroscience - San Diego, CA. 2016
    Donegan, J.J. and Lodge, D.J. Contribution of Hippocampal Projections to Discrete Symptoms of Schizophrenia - UTHSCSA Department of Pharmacology Graduate Student Symposium - San Antonio, TX. 2016
    Donegan, J.J., Boley, A.M., Lodge, D.J. Embryonic Stem Cell Transplants as a Therapeutic Strategy in a Rodent Model of Autism - Center for Biomedical Neurosciences Retreat - San Antonio, TX. 2016
    Donegan, J.J., Tyson, J.A., Branch, S.Y., Beckstead, M.J., Anderson, S.A., Lodge, D.J. Embryonic stem cell transplants as a therapeutic strategy in a rodent model of schizophrenia - Schizophrenia International Research Society - Florence, Italy 2016)
    Donegan, J.J., Tyson, J.A., Anderson, S.A., Lodge, D.J. Embryonic stem cell transplants as a therapeutic strategy in a rodent model of schizophrenia - Society for Neuroscience - Chicago, IL. 2015

Jennifer Donegan

Postdoctoral Fellow
Ph.D., Neuroscience
UTHSCSA
San Antonio, Texas

Lab: 210-567-4273
Email: donegan@uthscsa.edu
Lab Association: Daniel Lodge, Ph.D.

 
 

Research Interests

• schizophrenia                                   • stem cells
• dopamine
 

Research Summary

My research is exploring the use of embryonic stem cells to reverse deficits in a developmental model of schizophrenia. Schizophrenic patients show changes in inhibitory GABAergic interneurons, which are thought to underlie behavioral and physiological symptoms of the disorder. Using a battery of behavioral assays and in vivo extracellular electrophysiology, we are testing the hypothesis that GABAergic interneurons, derived from embryonic stem cells, can reverse the schizophrenia-like changes seen in our rodent model.

 
 

• Accomplishments, Awards and Honors •

UTHSA Center for Biomedical Neuroscience (CBN) Annual Retreat Poster Award - May 2016


Schizophrenia International Research Society Poster Award Finalist - April 2016


Schizophrenia International Research Society Travel Award - Feb 2016


UTHSA Pharmacology Graduate Student Symposium Poster Award - Nov 2015


William Thomas Booth Travel Award - UTHSCSA Pharmacology - August 2015


UTHSA Center for Biomedical Neuroscience (CBN) Annual Retreat Poster Award - May 2015


HSC News - 'Low levels of pro-inflammatory agent help cognition in rats' - Feb 2014


Society for Neuroscience (SfN) Meeting Travel Award - 2013



• Appointments, Boards, Committees, and Memberships •

Society for Neuroscience (SfN)



• Lectures and Presentations •

ASPET Undergraduate Research Program - Lecture on Synaptic Transmission - Summer 2014-2017


ASPET Undergraduate Research Program - Lecture on Cell Culture Techniques - Summer 2014-2017