The Physiology and Pharmacology Discipline encompasses the study of fundamental mechanisms of normal and disease function. Investigators seek to integrate information from molecular, cellular and organ/system levels to spur discoveries, which will lead to new and improved drug treatments for human and animal disease. Using sophisticated genetic and molecular tools, our scientists are unraveling the fundamental mechanisms that underlie tissue and cellular physiology, and how these processes are compromised in injury and disease. The University of Texas Health Science Center, San Antonio is renowned for its seminal contributions in many areas including cardiovascular physiology, neurophysiology and the physiological basis of aging. Using multidisciplinary approaches, our scientists are able to offer a unique perspective in determining the effects of chemical agents upon biological processes at the sub-cellular, cellular, organ system, physiological and behavioral levels; the ultimate goal is the treatment and prevention of disease. Internationally recognized research expertise is assembled in areas of neuropharmacology, cancer pharmacology, diabetes, addiction and pain research.